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Discrimination of Mumps Virus Small Hydrophobic Gene Deletion Effects from Gene Translation Effects on Virus Virulence

Deletion of the small hydrophobic (SH) protein of certain paramyxoviruses has been found to result in attenuation, suggesting that the SH protein is a virulence factor. To investigate the role of the mumps virus (MuV) SH protein in virulence, multiple stop codons were introduced into the open readin...

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Main Authors: Malik, Tahir, Shegogue, Candie Wolbert, Werner, Kellie, Ngo, Laurie, Sauder, Christian, Zhang, Cheryl, Duprex, William Paul, Rubin, Steven
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126307/
https://ncbi.nlm.nih.gov/pubmed/21471236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02686-10
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