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Gene-Specific Contributions to Mumps Virus Neurovirulence and Neuroattenuation

Mumps virus (MuV) is highly neurotropic and was the leading cause of aseptic meningitis in the Western Hemisphere prior to widespread use of live attenuated MuV vaccines. Due to the absence of markers of virus neuroattenuation and neurovirulence, ensuring mumps vaccine safety has proven problematic,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sauder, Christian J., Zhang, Cheryl X., Ngo, Laurie, Werner, Kellie, Lemon, Ken, Duprex, W. Paul, Malik, Tahir, Carbone, Kathryn, Rubin, Steven A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126569/
https://ncbi.nlm.nih.gov/pubmed/21543475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00245-11
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