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Early Embryonic Lethality Due to Targeted Inactivation of DNA Ligase III

DNA ligases catalyze the joining of strand breaks in the phosphodiester backbone of duplex DNA and play essential roles in DNA replication, recombination, repair, and maintenance of genomic integrity. Three mammalian DNA ligase genes have been identified, and their corresponding ligases play distinc...

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Detalles Bibliográficos
Main Authors: Puebla-Osorio, Nahum, Lacey, Devin B., Alt, Frederick W., Zhu, Chengming
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489003/
https://ncbi.nlm.nih.gov/pubmed/16648486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.10.3935-3941.2006
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