Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70

DNA double-strand breaks (DSBs) are recognized and repaired by the Classical Non-Homologous End-Joining (C-NHEJ) and Homologous Recombination pathways. C-NHEJ includes the core Ku70 and Ku80 (or Ku86) heterodimer that binds DSBs and thus promotes recruitment of accessory downstream NHEJ factors XLF,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:DNA Repair (Amst)
Main Authors: Xing, Mengtan, Bjørås, Magnar, Daniel, Jeremy A., Alt, Frederick W., Oksenych, Valentyn
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584571/
https://ncbi.nlm.nih.gov/pubmed/28759779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.07.008
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker