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Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA‐PKcs in human cells
DNA double‐strand breaks (DSBs) are highly cytotoxic lesions, and unrepaired or misrepaired DSBs can lead to various human diseases, including immunodeficiency, neurological abnormalities, growth retardation, and cancer. Nonhomologous end joining (NHEJ) is the major DSB repair pathway in mammals. Ku...
Tallennettuna:
| Julkaisussa: | FEBS Open Bio |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley and Sons Inc.
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609761/ https://ncbi.nlm.nih.gov/pubmed/31141305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12681 |
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