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Non-Homologous End Joining Factors XLF, PAXX and DNA-PKcs Maintain the Neural Stem and Progenitor Cell Population

Non-homologous end-joining (NHEJ) is a major DNA repair pathway in mammalian cells that recognizes, processes and fixes DNA damage throughout the cell cycle and is specifically important for homeostasis of post-mitotic neurons and developing lymphocytes. Neuronal apoptosis increases in the mice lack...

詳細記述

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書誌詳細
出版年:Biomolecules
主要な著者: Gago-Fuentes, Raquel, Oksenych, Valentyn
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823790/
https://ncbi.nlm.nih.gov/pubmed/33379193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11010020
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