Targeted gene repair directed by the chimeric RNA/DNA oligonucleotide in a mammalian cell-free extract.
Chimeric oligonucleotides consisting of RNA and DNA residues have been shown to catalyze site-directed genetic alteration in mammalian cells both in vitro and in vivo. Since the frequency of these events appears to be logs higher than the rates of gene targeting, a process involving homologous recom...
محفوظ في:
| الحاوية / القاعدة: | Nucleic Acids Res |
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| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Oxford University Press
1999
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9973621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.5.1323 |
| الوسوم: |
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