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Strand Bias in Targeted Gene Repair Is Influenced by Transcriptional Activity
Modified single-stranded DNA oligonucleotides can direct nucleotide exchange in Saccharomyces cerevisiae. Point and frameshift mutations are corrected in a reaction catalyzed by cellular enzymes involved in various DNA repair processes. The present model centers on the annealing of the vector to one...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133839/ https://ncbi.nlm.nih.gov/pubmed/11997519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3852-3863.2002 |
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