Strand Bias in Targeted Gene Repair Is Influenced by Transcriptional Activity

Modified single-stranded DNA oligonucleotides can direct nucleotide exchange in Saccharomyces cerevisiae. Point and frameshift mutations are corrected in a reaction catalyzed by cellular enzymes involved in various DNA repair processes. The present model centers on the annealing of the vector to one...

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Hlavní autoři: Liu, Li, Rice, Michael C., Drury, Miya, Cheng, Shuqiu, Gamper, Howard, Kmiec, Eric B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC133839/
https://ncbi.nlm.nih.gov/pubmed/11997519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3852-3863.2002
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