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Strand Bias in Targeted Gene Repair Is Influenced by Transcriptional Activity

Modified single-stranded DNA oligonucleotides can direct nucleotide exchange in Saccharomyces cerevisiae. Point and frameshift mutations are corrected in a reaction catalyzed by cellular enzymes involved in various DNA repair processes. The present model centers on the annealing of the vector to one...

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Publicat a:Mol Cell Biol
Autors principals: Liu, Li, Rice, Michael C., Drury, Miya, Cheng, Shuqiu, Gamper, Howard, Kmiec, Eric B.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133839/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997519/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.11.3852-3863.2002
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