Sequence-Resolved Detection of Pausing by Single RNA Polymerase Molecules

Transcriptional pausing by RNA polymerase (RNAP) plays an important role in the regulation of gene expression. Defined, sequence-specific pause sites have been identified biochemically. Single-molecule studies have also shown that bacterial RNAP pauses frequently during transcriptional elongation, b...

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Библиографические подробности
Главные авторы: Herbert, Kristina M., La Porta, Arthur, Wong, Becky J., Mooney, Rachel A., Neuman, Keir C., Landick, Robert, Block, Steven M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483142/
https://ncbi.nlm.nih.gov/pubmed/16777599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.04.032
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