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E. coli NusG Inhibits Backtracking and Accelerates Pause-free Transcription by Promoting Forward Translocation of RNA Polymerase

NusG is an essential transcription factor in E. coli that is capable of increasing the overall rate of transcription. Transcript elongation by RNA polymerase (RNAP) is frequently interrupted by pauses of varying durations, and NusG is known to decrease the occupancy of at least some paused states. H...

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Autors principals: Herbert, Kristina M., Zhou, Jing, Mooney, Rachel A., La Porta, Arthur, Landick, Robert, Block, Steven M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875378/
https://ncbi.nlm.nih.gov/pubmed/20381500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.051
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