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Sequence-Dependent Pausing of Single Lambda Exonuclease Molecules
Lambda exonuclease processively degrades one strand of duplex DNA, moving 5′-to-3′ in an ATP-independent fashion. When examined at the single-molecule level, the speeds of digestion were nearly constant at 4 nanometers per second (12 nucleotides per second), interspersed with pauses of variable dura...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1539570/ https://ncbi.nlm.nih.gov/pubmed/12947034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1088047 |
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