Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions

The BRCA2 tumor suppressor plays an important role in the repair of DNA damage by homologous recombination, also termed homology-directed repair (HDR). Human BRCA2 is 3,418 aa and is composed of several domains. The central part of the protein contains multiple copies of a motif that binds the Rad51...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Saeki, Hiroshi, Siaud, Nicolas, Christ, Nicole, Wiegant, Wouter W., van Buul, Paul P. W., Han, Mingguang, Zdzienicka, Małgorzata Z., Stark, Jeremy M., Jasin, Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482653/
https://ncbi.nlm.nih.gov/pubmed/16731627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600298103
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi