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Restriction beyond the restriction point: mitogen requirement for G(2 )passage

Cell proliferation is dependent on mitogenic signalling. When absent, normal cells cannot pass the G(1 )restriction point, resulting in cell cycle arrest. Passage through the G(1 )restriction point involves inactivation of the retinoblastoma protein family. Consequently, loss of the retinoblastoma p...

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Bibliografiske detaljer
Main Authors: Foijer, Floris, te Riele, Hein
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481568/
https://ncbi.nlm.nih.gov/pubmed/16759363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-1-8
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