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Restriction beyond the restriction point: mitogen requirement for G(2 )passage

Cell proliferation is dependent on mitogenic signalling. When absent, normal cells cannot pass the G(1 )restriction point, resulting in cell cycle arrest. Passage through the G(1 )restriction point involves inactivation of the retinoblastoma protein family. Consequently, loss of the retinoblastoma p...

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Autori principali: Foijer, Floris, te Riele, Hein
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481568/
https://ncbi.nlm.nih.gov/pubmed/16759363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-1-8
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