Ablation of the Retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

The retinoblastoma suppressor pRB belongs to the family of so-called pocket proteins, which also includes p107 and p130. These proteins may functionally overlap in cell cycle control and tumor suppression. We have generated an isogenic set of embryonic stem (ES) cell lines carrying single or compoun...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Genes Dev
Päätekijät:	Dannenberg, Jan-Hermen, van Rossum, Agnes, Schuijff, Leontine, te Riele, Hein
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Cold Spring Harbor Laboratory Press 2000
Aiheet:	Research Paper
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317114/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11114893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.847700
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