Ablation of the Retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
The retinoblastoma suppressor pRB belongs to the family of so-called pocket proteins, which also includes p107 and p130. These proteins may functionally overlap in cell cycle control and tumor suppression. We have generated an isogenic set of embryonic stem (ES) cell lines carrying single or compoun...
সংরক্ষণ করুন:
| প্রকাশিত: | Genes Dev |
|---|---|
| প্রধান লেখক: | , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Cold Spring Harbor Laboratory Press
2000
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317114/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11114893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.847700 |
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