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Signal amplification of padlock probes by rolling circle replication.

Circularizing oligonucleotide probes (padlock probes) have the potential to detect sets of gene sequences with high specificity and excellent selectivity for sequence variants, but sensitivity of detection has been limiting. By using a rolling circle replication (RCR) mechanism, circularized but not...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Banér, J, Nilsson, M, Mendel-Hartvig, M, Landegren, U
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC147976/
https://ncbi.nlm.nih.gov/pubmed/9801302
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