Signal amplification of padlock probes by rolling circle replication.

Circularizing oligonucleotide probes (padlock probes) have the potential to detect sets of gene sequences with high specificity and excellent selectivity for sequence variants, but sensitivity of detection has been limiting. By using a rolling circle replication (RCR) mechanism, circularized but not...

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Bibliografske podrobnosti

izdano v:	Nucleic Acids Res
Principais autores:	Banér, J, Nilsson, M, Mendel-Hartvig, M, Landegren, U
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 1998
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9801302/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.22.5073
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