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Signal amplification of padlock probes by rolling circle replication.

Circularizing oligonucleotide probes (padlock probes) have the potential to detect sets of gene sequences with high specificity and excellent selectivity for sequence variants, but sensitivity of detection has been limiting. By using a rolling circle replication (RCR) mechanism, circularized but not...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Banér, J, Nilsson, M, Mendel-Hartvig, M, Landegren, U
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147976/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9801302/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.22.5073
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