Signal amplification of padlock probes by rolling circle replication.
Circularizing oligonucleotide probes (padlock probes) have the potential to detect sets of gene sequences with high specificity and excellent selectivity for sequence variants, but sensitivity of detection has been limiting. By using a rolling circle replication (RCR) mechanism, circularized but not...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1998
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9801302/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.22.5073 |
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