Signal amplification of padlock probes by rolling circle replication.

Circularizing oligonucleotide probes (padlock probes) have the potential to detect sets of gene sequences with high specificity and excellent selectivity for sequence variants, but sensitivity of detection has been limiting. By using a rolling circle replication (RCR) mechanism, circularized but not...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Banér, J, Nilsson, M, Mendel-Hartvig, M, Landegren, U
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1998
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9801302/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.22.5073
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