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Mechanism for allosteric inhibition of an ATP-sensitive ribozyme.

We report the structural basis for the modulation of an ATP-sensitive ribozyme that was engineered by modular rational design. This allosteric ribozyme is composed of two independently functioning domains, one a receptor for ATP and the other a self-cleaving ribozyme. When fused in the appropriate f...

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Bibliographic Details
Main Authors: Tang, J, Breaker, R R
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC147823/
https://ncbi.nlm.nih.gov/pubmed/9722642
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