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Mechanism of Feedback Allosteric Inhibition of ATP Phosphoribosyltransferase
[Image: see text] MtATP-phosphoribosyltransferase catalyzes the first and committed step in l-histidine biosynthesis in Mycobacterium tuberculosis and is therefore subjected to allosteric feedback regulation. Because of its essentiality, this enzyme is being studied as a potential target for novel a...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466779/ https://ncbi.nlm.nih.gov/pubmed/22989207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300808b |
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