Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.

PU.1 and C/EBPalpha are transcription factors essential for normal myeloid development. Loss-of-function mutation of PU.1 leads to an absolute block in monocyte/macrophage development and abnormal granulocytic development while that of C/EBPalpha causes a selective block in neutrophilic differentiat...

Full description

Saved in:
Bibliographic Details
Main Authors: Iwama, A, Zhang, P, Darlington, G J, McKercher, S R, Maki, R, Tenen, D G
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC147647/
https://ncbi.nlm.nih.gov/pubmed/9611252
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items