Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.

PU.1 and C/EBPalpha are transcription factors essential for normal myeloid development. Loss-of-function mutation of PU.1 leads to an absolute block in monocyte/macrophage development and abnormal granulocytic development while that of C/EBPalpha causes a selective block in neutrophilic differentiat...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Iwama, A, Zhang, P, Darlington, G J, McKercher, S R, Maki, R, Tenen, D G
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC147647/
https://ncbi.nlm.nih.gov/pubmed/9611252
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