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Effects of phosphate neutralization on the shape of the AP-1 transcription factor binding site in duplex DNA.

Previous electrophoretic experiments suggest that the AP-1 site in duplex DNA bends in response to the pattern of amino acid charges distal to the basic region in bound bZIP proteins. The extent and direction of apparent DNA bending are consistent with the prediction that DNA will collapse locally u...

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Autors principals: Tomky, L A, Strauss-Soukup, J K, Maher, L J
Format: Artigo
Idioma:Inglês
Publicat: 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC147564/
https://ncbi.nlm.nih.gov/pubmed/9580678
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