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AP-1 Binding Transcriptionally Regulates Human Neutral Ceramidase
Many forms of cellular stress cause an elevation of endogenous ceramide levels leading to growth arrest or apoptosis. Ceramidases (CDase) play a critical role in regulating apoptosis by hydrolyzing ceramide into sphingosine, a precursor for promitogenic sphingosine-1-phosphate. Growth factor inducti...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762565/ https://ncbi.nlm.nih.gov/pubmed/21530485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.04.009 |
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