Selective inhibition of cell-free translation by oligonucleotides targeted to a mRNA hairpin structure.
Using an in vitro selection approach we have previously isolated oligodeoxy aptamers that can bind to a DNA hairpin structure without disrupting the double-stranded stem. We report here that these oligomers can bind to the RNA version of this hairpin, mostly through pairing with a designed 6 nt anch...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9580674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.10.2273 |
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