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Selective inhibition of cell-free translation by oligonucleotides targeted to a mRNA hairpin structure.

Using an in vitro selection approach we have previously isolated oligodeoxy aptamers that can bind to a DNA hairpin structure without disrupting the double-stranded stem. We report here that these oligomers can bind to the RNA version of this hairpin, mostly through pairing with a designed 6 nt anch...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Le Tinévez, R, Mishra, R K, Toulmé, J J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147550/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9580674/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.10.2273
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