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Selective inhibition of cell-free translation by oligonucleotides targeted to a mRNA hairpin structure.

Using an in vitro selection approach we have previously isolated oligodeoxy aptamers that can bind to a DNA hairpin structure without disrupting the double-stranded stem. We report here that these oligomers can bind to the RNA version of this hairpin, mostly through pairing with a designed 6 nt anch...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Le Tinévez, R, Mishra, R K, Toulmé, J J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC147550/
https://ncbi.nlm.nih.gov/pubmed/9580674
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