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Oligo-[alpha]-deoxynucleotides covalently linked to an intercalating agent. Double helices with parallel strands are formed with complementary oligo-[beta]-deoxynucleotides.

An oligo-[alpha]-deoxynucleotide of sequence (5')d(TCTAAACTC) (3') was synthesized using the alpha-anomers of deoxynucleosides and its 5'-phosphate was covalently linked to a 9-amino acridine derivative via a pentamethylene linker. Two oligo-[beta]-deoxynucleotides containing the comp...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nucleic Acids Res
Main Authors: Sun, J S, Asseline, U, Rouzaud, D, Montenay-Garestier, T, Nguyen, T T, Hélène, C
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 1987
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3627982/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.15.6149
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