Oligo-[alpha]-deoxynucleotides covalently linked to an intercalating agent. Double helices with parallel strands are formed with complementary oligo-[beta]-deoxynucleotides.

An oligo-[alpha]-deoxynucleotide of sequence (5')d(TCTAAACTC) (3') was synthesized using the alpha-anomers of deoxynucleosides and its 5'-phosphate was covalently linked to a 9-amino acridine derivative via a pentamethylene linker. Two oligo-[beta]-deoxynucleotides containing the complementary seque...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Sun, J S, Asseline, U, Rouzaud, D, Montenay-Garestier, T, Nguyen, T T, Hélène, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1987
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3627982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.15.6149
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