Enzymatic mutation detection. Procedure for screening and mapping of mutations by immobilised endonuclease VII.
Endonuclease VII (endo VII) binds to non-pairing nucleotides in DNA. This served as the basis for the development of a mutation detection assay involving immobilised endo VII and heteroduplex DNAs made by hybridisation of mutant and wild type DNA. The use of microtiter plates allows screening of lar...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147345/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9461481/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.4.1132 |
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