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Screening for mutations by enzyme mismatch cleavage with T4 endonuclease VII.

Each of four possible sets of mismatches (G.A/C.T, C.C/G.G, A.A/T.T, and C.A/G.T) containing the 8 possible single-base-pair mismatches derived from isolated mutations were examined to test the ability of T4 endonuclease VII to consistently detect mismatches in heteroduplexes. At least two examples...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Youil, R, Kemper, B W, Cotton, R G
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816853/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.1.87
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