Enzymatic mutation detection. Procedure for screening and mapping of mutations by immobilised endonuclease VII.

Endonuclease VII (endo VII) binds to non-pairing nucleotides in DNA. This served as the basis for the development of a mutation detection assay involving immobilised endo VII and heteroduplex DNAs made by hybridisation of mutant and wild type DNA. The use of microtiter plates allows screening of lar...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Golz, S, Birkenkamp-Demtröder, K, Kemper, B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1998
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147345/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9461481/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.4.1132
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