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Enzymatic mutation detection. Procedure for screening and mapping of mutations by immobilised endonuclease VII.

Endonuclease VII (endo VII) binds to non-pairing nucleotides in DNA. This served as the basis for the development of a mutation detection assay involving immobilised endo VII and heteroduplex DNAs made by hybridisation of mutant and wild type DNA. The use of microtiter plates allows screening of lar...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Golz, S, Birkenkamp-Demtröder, K, Kemper, B
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147345/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9461481/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.4.1132
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