2'-Deoxynucleoside 5'-triphosphates modified at alpha-, beta- and gamma-phosphates as substrates for DNA polymerases.

Replacement of alpha-, beta- and gamma-phosphate groups in 2'-deoxynucleoside 5'-triphosphates (dNTP) with phosphonate groups yields a new set of dNTP mimics with potential biological and therapeutic applications. Here, we describe the synthesis of 15 new dNTPs modified at alpha-, beta- and gamma-ph...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Alexandrova, L A, Skoblov, A Y, Jasko, M V, Victorova, L S, Krayevsky, A A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1998
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9443970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.3.778
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!