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2'-Deoxynucleoside 5'-triphosphates modified at alpha-, beta- and gamma-phosphates as substrates for DNA polymerases.

Replacement of alpha-, beta- and gamma-phosphate groups in 2'-deoxynucleoside 5'-triphosphates (dNTP) with phosphonate groups yields a new set of dNTP mimics with potential biological and therapeutic applications. Here, we describe the synthesis of 15 new dNTPs modified at alpha-, beta- and gamma-ph...

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Publicado no:Nucleic Acids Res
Principais autores: Alexandrova, L A, Skoblov, A Y, Jasko, M V, Victorova, L S, Krayevsky, A A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147325/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9443970/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.3.778
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