2'-Deoxynucleoside 5'-triphosphates modified at alpha-, beta- and gamma-phosphates as substrates for DNA polymerases.

Replacement of alpha-, beta- and gamma-phosphate groups in 2'-deoxynucleoside 5'-triphosphates (dNTP) with phosphonate groups yields a new set of dNTP mimics with potential biological and therapeutic applications. Here, we describe the synthesis of 15 new dNTPs modified at alpha-, beta- and gamma-ph...

Full description

Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Alexandrova, L A, Skoblov, A Y, Jasko, M V, Victorova, L S, Krayevsky, A A
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 1998
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9443970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.3.778
Tags:	Add Tag No Tags, Be the first to tag this record!