Solution structure of a highly stable DNA duplex conjugated to a minor groove binder.
The tripeptide 1,2-dihydro-(3 H )-pyrrolo[3,2- e ]indole-7-carboxylate (CDPI3) binds to the minor groove of DNA with high affinity. When this minor groove binder is conjugated to the 5'-end of short oligonucleotides the conjugates form unusually stable hybrids with complementary DNA and thus may hav...
Gorde:
| Argitaratua izan da: | Nucleic Acids Res |
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| Egile Nagusiak: | , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
1998
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9443977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.3.831 |
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