लोड हो रहा है...
3′-Azido-3′-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: A possible mechanism of AZT hepatotoxicity
3′-Azido-3′-deoxythymidine (AZT) is a staple of highly active antiretroviral therapy (HAART). Prior to HAART, long-term use of high-dosage AZT caused myopathy, cardiomyopathy, and hepatotoxicity, associated with mitochondrial DNA depletion. As a component of HARRT, AZT causes cytopenias and lipodyst...
में बचाया:
मुख्य लेखकों: | , , |
---|---|
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2006
|
विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472706/ https://ncbi.nlm.nih.gov/pubmed/16472780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2006.01.003 |
टैग : |
टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|