Phosphorylation of Thymidine and AZT in Heart Mitochondria: Elucidation of a Novel Mechanism of AZT Cardiotoxicity

Antiretroviral nucleoside analogs used in highly active antiretroviral therapy (HAART) are associated with cardiovascular and other tissue toxicity associated with mitochondrial DNA depletion, suggesting a block in mitochondrial (mt)-DNA replication. Because the triphosphate forms of these analogs v...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: McKee, Edward E., Bentley, Alice T., Hatch, Matthew, Gingerich, Joel, Susan-Resiga, Delia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2004
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472705/
https://ncbi.nlm.nih.gov/pubmed/15371631
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak