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Proteomic Study of Peptide Deformylase Inhibition in Streptococcus pneumoniae and Staphylococcus aureus

Peptide deformylase (PDF) is an essential enzyme in both gram-negative and gram-positive bacteria. It hydrolyzes formylated N-terminal peptides to generate free N-terminal peptides during the process of protein maturation. Inhibition of this enzyme results in cessation of bacterial growth. We have e...

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Autores principales: Wang, Wen, White, Richard, Yuan, Zhengyu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472206/
https://ncbi.nlm.nih.gov/pubmed/16641432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1656-1663.2006
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