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Molecular Determinants of Substrate Specificity for Semliki Forest Virus Nonstructural Protease

The C-terminal cysteine protease domain of Semliki Forest virus nonstructural protein 2 (nsP2) regulates the virus life cycle by sequentially cleaving at three specific sites within the virus-encoded replicase polyprotein P1234. The site between nsP3 and nsP4 (the 3/4 site) is cleaved most efficient...

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Библиографические подробности
Главные авторы: Lulla, Aleksei, Lulla, Valeria, Tints, Kairit, Ahola, Tero, Merits, Andres
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472149/
https://ncbi.nlm.nih.gov/pubmed/16699022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00229-06
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