Minor groove DNA alkylation directed by major groove triplex forming oligodeoxyribonucleotides.
We describe sequence-specific alkylation in the minor groove of double-stranded DNA by a hybridization-triggered reactive group conjugated to a triplex forming oligodeoxyribonucleotide (TFO) that binds in the major groove. The 24 nt TFOs (G/A motif) were designed to form triplexes with a homopurine...
में बचाया:
| में प्रकाशित: | Nucleic Acids Res |
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| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
1997
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147161/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9396819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.24.5077 |
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