Sequence-specific targeting and covalent modification of human genomic DNA.

We compare two techniques which enable selective, nucleotide-specific covalent modification of human genomic DNA, as assayed by quantitative ligation- mediated PCR. In the first, a purine motif triplex-forming oligonucleotide with a terminally appended chlorambucil was shown to label a target guanin...

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Bibliografische Detailangaben

Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Belousov, E S, Afonina, I A, Podyminogin, M A, Gamper, H B, Reed, M W, Wydro, R M, Meyer, R B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9254701/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.17.3440
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