Sequence-specific targeting and covalent modification of human genomic DNA.
We compare two techniques which enable selective, nucleotide-specific covalent modification of human genomic DNA, as assayed by quantitative ligation- mediated PCR. In the first, a purine motif triplex-forming oligonucleotide with a terminally appended chlorambucil was shown to label a target guanin...
Uloženo v:
| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9254701/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.17.3440 |
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