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Detection of covalent triplex within human cells.

Triple helix-forming oligonucleotides covalently linked to psoralen can be specifically cross-linked to both strands of DNA at the triplex-duplex junction following UV irradiation. We have previously shown that a 15mer psoralen-oligonucleotide conjugate forming a triple helix on the promoter of the...

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Autors principals: Guieysse, A L, Praseuth, D, Grigoriev, M, Harel-Bellan, A, Hélène, C
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC146220/
https://ncbi.nlm.nih.gov/pubmed/8932374
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