Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase.

Human immunodeficiency virus type 1 (HIV-1) variants with resistance mutations in the reverse transcriptase (RT) gene appear during drug therapy with the nucleoside analogue 2',3'-dideoxy-3'-thiacytidine (3TC). These 3TC-resistant RT variants have a single point mutation that changes the 184Met resi...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Oude Essink, B B, Back, N K, Berkhout, B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9241233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.16.3212
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