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Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase.

Human immunodeficiency virus type 1 (HIV-1) variants with resistance mutations in the reverse transcriptase (RT) gene appear during drug therapy with the nucleoside analogue 2',3'-dideoxy-3'-thiacytidine (3TC). These 3TC-resistant RT variants have a single point mutation that changes...

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Detalhes bibliográficos
Main Authors: Oude Essink, B B, Back, N K, Berkhout, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146883/
https://ncbi.nlm.nih.gov/pubmed/9241233
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