Synthesis and binding properties of conjugates between oligodeoxynucleotides and daunorubicin derivatives.
Conjugation of an anthracycline to a triplex-forming oligonucleotide (TFO) allows delivery of this drug to a specific DNA site, preserving the intercalation geometry of this class of anticancer agents. Conjugate 11, in which the TFO is linked via a hexamethylene bridge to the O-4 on the D ring of th...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
1997
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9153311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.11.2121 |
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