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Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation

The exon–junction complex (EJC) components hUpf3a and hUpf3b serve a dual function: They promote nonsense-mediated mRNA decay (NMD), and they also regulate translation efficiency. Whether these two functions are interdependent or independent of each other is unknown. We characterized the function of...

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Bibliografiske detaljer
Main Authors: Kunz, Joachim B., Neu-Yilik, Gabriele, Hentze, Matthias W., Kulozik, Andreas E., Gehring, Niels H.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464862/
https://ncbi.nlm.nih.gov/pubmed/16601204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.12506
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