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Predicting stochastic gene expression dynamics in single cells

Fluctuations in protein numbers (noise) due to inherent stochastic effects in single cells can have large effects on the dynamic behavior of gene regulatory networks. Although deterministic models can predict the average network behavior, they fail to incorporate the stochasticity characteristic of...

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Библиографические подробности
Главные авторы: Mettetal, Jerome T., Muzzey, Dale, Pedraza, Juan M., Ozbudak, Ertugrul M., van Oudenaarden, Alexander
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464336/
https://ncbi.nlm.nih.gov/pubmed/16648266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509874103
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